Funny you should mention this... my elderly FIL is rehabbing at home after surgery and one of the visiting nurses is very large, at least 300lbs. His first visit he told us to all mask up because we weren’t vaccinated - but we have all been exposed to covid many times, FIL especially, and if we had it, it was not more than a head cold.
The nurse is genuinely scared of us, and sadly (I can never tell him this of course), he is a lot more at risk from his weight than from us.
But I work with overweight others all the time.
In fact most Hosp. folk I know are overweight. Some very Obese.....