NAC, as a treatment for Covid, may indiscriminately destroy the biofilm of the good bacteria in our microbiome.
“NAC, in combination with different antibiotics, significantly promoted their permeability to the deepest layers of the biofilm”
https://pubmed.ncbi.nlm.nih.gov/25339490/
Is that your conclusion? I do not see that in the abstract. I don't have an account so can't see the entire paper.
Results: The studies analyzed, with score over 3, suggested a potential role for NAC as adjuvant molecule in the treatment of bacterial biofilms, with an excellent safety and efficacy profile. NAC, in combination with different antibiotics, significantly promoted their permeability to the deepest layers of the biofilm, overcoming the problem of the resistance to the classic antibacterial therapeutic approach.
Conclusions: Overall, these results are encouraging to a more widespread clinical use of NAC, as adjuvant therapy for microbial infections followed by biofilm settle, which may occur in several body districts, such as the vaginal cavity.
NAC, as a treatment for Covid, may indiscriminately destroy the biofilm of the good bacteria in our microbiome.
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I came to a different conclusion when I read the results of the study in the link. The biofilms referred to in the article seem to be those of harmful bacteria. FTA:
“Biofilms are microbial communities consisting of bacteria, extremely capable to self-reproduce on biological surfaces, causing infections. Frequently, these biofilms are resistant to classical antibacterial treatments and host immune response. Thus, adjuvant molecules are mandatory in clinical practice. [NAC], a precursor to the antioxidant glutathione, has been investigated for its effectiveness both in inhibiting biofilm formation and in destroying developed biofilms.”
The results of the study “suggested a potential role for NAC as adjuvant molecule in the treatment of bacterial biofilms, with an excellent safety and efficacy profile. NAC, in combination with different antibiotics, significantly promoted their permeability to the deepest layers of the biofilm, overcoming the problem of the resistance to the classical antibacterial therapeutic approach. Overall, these results are encouraging to a more widespread clinical use of NAC, as adjuvant therapy for microbial infections ...”
NAC, as a treatment for Covid, may indiscriminately destroy the biofilm of the good bacteria in our microbiome.
“NAC, in combination with different antibiotics, significantly promoted their permeability to the deepest layers of the biofilm”
https://pubmed.ncbi.nlm.nih.gov/25339490/