Uh, no. Mr. Burns’ character, appearance, and mannerisms are based on several different people. The show’s creator Matt Groening principally based Mr. Burns on his high school teacher Mr. Bailey. Drawing further inspiration from oil tycoon John D. Rockefeller, David Rockefeller, Groening made Mr. Burns the “embodiment of corporate greed”.Animator David Silverman parodied Mr. Burns’ appearance on Fox founder Barry Diller, and modeled his body on a praying mantis.The idea of Mr. Burns reading employee names off cards in “There’s No Disgrace Like Home” came from an article about Ronald Reagan that writer Al Jean had read.In some episodes, parallels have been drawn between Mr. Burns and moguls such as Howard Hughes and, more frequently, fictional character Charles Foster Kane from Citizen Kane.
There is a poignant scene with burns/smithers, with CLEAR references to burns maintaining his youth using adrenochrome from a “little boy”.
I’m going with a Rothschild.