grey_whiskers wrote:
“
A grant proposal from Daszak in 2018.
“We will collect viral load data from fresh fecal pellets. SARSr-CoV spike proteins will be sequenced, viral recombination events identified, and isolates used to deny strains that can replicate in human cells. The Univ. N Carolina (UNC) team will reverse engineer spike proteins of a large sample of high and low-risk viruses for further characterization. This will effectively freeze the QS we analyze at t=0. These QS0 strain viral spike glycoproteins will be synthesized and those binding to human cell receptor ACE2 will be inserted into SARSr-CoV backbones (non DURC, non-GoF), and inoculated into humanized mice to assess capacity o cause SARS like disease, efficay of monoclonal therapies, the inhibitor G-57348 or vaccines against SARS-Cov8-12. “
https://s3.documentcloud.org/documents/21066966/defuse-proposal.pdf
“
Where did that research go, after UNC?
Outsourced to Wuhan when told they couldn’t do gain-of-function research in the US?
Page 26 shows the lead investigators. https://s3.documentcloud.org/documents/21066966/defuse-proposal.pdf
T Rocke’s publications...https://pubmed.ncbi.nlm.nih.gov/?sort=date&term=Rocke+TE&cauthor_id=33897819
Jerome Unidad He specializes in aerosol spray delivery systems. Nothingon Pubmed.
The prolific Shi... https://pubmed.ncbi.nlm.nih.gov/?term=shi+zheng-li&sort=date
Wang...https://pubmed.ncbi.nlm.nih.gov/?term=Wang%20Linfa&sort=date&page=2
Baric...https://pubmed.ncbi.nlm.nih.gov/?term=Baric%20Ralph&sort=date
Daszak...https://pubmed.ncbi.nlm.nih.gov/?term=Daszak+Peter&sort=date
This one looks like it’s from the grant...Daszak and Wang...A strategy to assess spillover risk of bat SARS-related coronaviruses in Southeast Asia.
Sánchez CA, Li H, Phelps KL, Zambrana-Torrelio C, Wang LF, Olival KJ, Daszak P. medRxiv. 2021 Sep 14:2021.09.09.21263359. doi: 10.1101/2021.09.09.21263359. Preprint. PMID: 34545371 Free PMC article. https://www.medrxiv.org/content/10.1101/2021.09.09.21263359v1.full.pdf+html