“Send her on a fact finding trip to Afghanistan!”
And other assorted armpits of the world.
Just tell Kammie her job for the next three years will be taking trips to such exotic locales as Botswana, the Congo, Haiti, Libya, Burundi, Liberia, Somalia and Malawi. Her US stops could include Barrow, Alaska and other hospitable environs.
There are ways of “asking” for resignations.
It appears Xho Bhi Din already did that. It appears that Kamala told him to "piss up a rope, Grandpa", or words to that effect.
The VP does not serve at the pleasure of the President, and the Constitutional duty of the VP isn't to do whatever the President says. That's just a convention.