Free Republic
Browse · Search
General/Chat
Topics · Post Article

To: PIF

Here’s the bottom line. The cell organelle that makes the protein that destroys neurons is controlled by an enzyme known as SIGMAR-1. Increase SIGMAR-1 blocks a critical receptor and the toxic protein is blocked from production. Healthy people produce SIGMAR-1 most of their life but it declines with age and severely declines with Alzheimer’s patients.

Currently the leading drug candidate that does exactly this is Anavex Lifesciences AVX-273 clinical trial.


29 posted on 10/18/2021 8:39:17 AM PDT by Dave Wright
[ Post Reply | Private Reply | To 2 | View Replies ]


To: Dave Wright

There are many theories, by non-scientists, about the “cause” of Alzheimers. Besides age or genetics, what other factors trigger the process identified by these brilliant researchers? Sugar, bad fatty diet, concussions, modern American education?


96 posted on 10/20/2021 10:51:25 AM PDT by The Westerner (Protect the most vulnerable: get the gov out of medicine, education and forests!)
[ Post Reply | Private Reply | To 29 | View Replies ]

Free Republic
Browse · Search
General/Chat
Topics · Post Article


FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson