The Massachusetts case is irrelevant, that was a state/local code, this issue will turn on whether the federal government has the power, far less clear. But on the other hand, it’s already been well-established that a private company can fire someone for nothing getting vaxxed, so there’s no case there, so far as I’m aware.
No government mandated medical procedure should be tolerated, especially one that is experimental.
What’s next?
Mandatory spay and neuter for conservatives?
Wrongful termination, bankrupt the company fighting the lawsuits. Plus if they did not give or allow immunity, medical, or religious exemption, seems like issues.