re ivermectin and alcohol, please be aware.....
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https://www.drugs.com/food-interactions/ivermectin.html?professional=1
Ivermectin and Alcohol/Food Interactions
Moderate
Alcohol (Ethanol)
ivermectin
GENERALLY AVOID: Alcohol may increase the plasma concentrations of ivermectin. The mechanism of interaction is unknown. In 20 healthy, nonsmoking patients with onchocerciasis, mean plasma ivermectin concentrations at 1, 3 and 4 hours post-dose (150 mcg/kg) were approximately 34% to 40% higher in the group given the medication with 750 mL of beer (4.5% v/v alcohol) than in controls who ingested the medication with water. There were no side effects in either study or control subjects. However, there have been anecdotal reports of increased central nervous system adverse effects and postural hypotension in patients who combined ivermectin with alcohol.
MANAGEMENT: Patients receiving ivermectin therapy should preferably avoid the consumption of alcohol to prevent any undue adverse effects of ivermectin.
References
Pollak PT, Slayter KL “Reduced serum theophylline concentrations after discontinuation of azithromycin: evidence for an unusual interaction.” Pharmacotherapy 17 (1997): 827-9
Chijioke CP, Okonkwo PO “Adverse events following mass ivermectin therapy for onchocerciasis.” Trans R Soc Trop Med Hyg 86 (1992): 284-6
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FWIW reports also suggest that ivermection may be of utility in treating alcohol addiction.
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