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To: Bayard

12 mg / day for 5 days is what the literature has reported. But please do not delay getting actual early treatment with monoclonals such as regeneron which is a superior treatment once diagnosed with CoVId.

I do not support the use of ivermectin as in my experience and judgment if does not help. I saw one late case which it might have but I am aware several freepers stake their nonclinical reputation on this. I am providing the correct dose to avoid potential overdose of this drug. Additionally procuring human ivermectin would be preferable to horse paste.


26 posted on 08/20/2021 1:42:50 PM PDT by gas_dr (Conditions of Socratic debate: Intelligence, Candor, and Good Will. )
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To: gas_dr

there are tons of reports that it does work- even peer reviewed studies done to that effect- does it help everyone 100%? Nope- but does it work in certain circumstances? Fro m the literature and studies and papers, it seems to-

However, you are right to seek tradition help as well, no reason the two can’t be down together- especially if studies are showing ivermectin dopes help- with something like covid- you would want to have every advantage you can if you have other illnesses- so it would seem adding a mostly safe drug to the traditional medicines isn’t going to hurt if taken in correct doses- if it doesn’t help, along with traditional meds, then meh- we (the one taking both approaches) ‘gave it all we could’ to try to prevent serious illness-


39 posted on 08/20/2021 2:00:34 PM PDT by Bob434
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To: gas_dr; NoLibZone

“This syringe contains sufficient paste to treat one 1250 lb horse at the recommended dose rate of 91 mcg ivermectin per lb (200 mcg/kg) body weight.” That is from the information sheet on the horse paste product. If my math is right - check it! - 91 mcg times 1250 gives 113,750 mcg or 114 mg/tube.

The literature uses 12 mg/day for 5 days. That would be just over 1/10th of a tube, so a standard dose for a 130 lb horse! A 170 lb man taking it at the standard rate for a horse would get 15.5 mg dose instead of 12....probably an insignificant difference (200.5 mcg/kg versus 200? Check my math please.). A dose based on weight makes more sense to me.

“A study was carried out in southeastern Gabon to evaluate the tolerance and efficacy of single high doses of ivermectin in 31 Loa loa-infected subjects with low-to-moderate parasitemia (7-7,700 microfilaria/ml). The first group of 16 subjects received 300 micrograms/kg of ivermectin and, seven days later, a second group of 15 received 400 micrograms/kg. Complete clinical and biological monitoring was carried out during the first 10 days post-treatment and again after one and three months. All subjects continued with their usual activities during the study. The clinical tolerance of treatment was very good, and except in one case, only mild adverse reactions were observed, with pruritus being the most common symptom. There were no significant changes in blood or urine function test results or in hematologic results, except for a pronounced eosinophil reaction. The 400 micrograms/kg dose of ivermectin equaled or surpassed in tolerance that of 300 micrograms/kg dose.”

https://pubmed.ncbi.nlm.nih.gov/8447521/

“A double blind, randomised, placebo controlled clinical trial was conducted to assess the safety and tolerability of oral subacute repeat doses of up to 1.2 mg/kg bw and an acute dose of 2.0 mg/kg bw in 68 healthy adult male and female human subjects as a treatment for headlice. No treatment related signs of toxicity were observed...”

https://www.ema.europa.eu/en/documents/mrl-report/ivermectin-modification-maximum-residue-limits-summary-report-5-committee-veterinary-medicinal_en.pdf

Looks like it has been tested on humans at rates twice of what a standard horse paste tube (ADJUSTED FOR HUMAN WEIGHT) gives. 1250 lbs/tube, adjust for bodyweight.


88 posted on 08/20/2021 5:50:42 PM PDT by Mr Rogers
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