“Space-time is defined by the way objects interact.”
If something did not, does not, and will not interact with anything else, in what practical sense does it exist at all, from the perspective of anything else? Interaction defines existence.
Either something is measurable, repeatable, and testable or it’s B.S. unless it’s a guess at something that happened previously (creationism, evolution, continental drift).
But only that which can be measured matters IMHO.
Have you just created a new philosophy: Interactionism?
Precisely. It’s why the laws of physics—no matter what they are—apply to everything that exists. Period. Full stop.
Our models of the laws of physics can be wrong. But finding something that apparently “breaks” them is just the way we discover that fact.