In a nutshell what he’s saying is that putting the segment of the population in the “active immunity” phase of their life where it’d be nothing to mild flu level into the vaccination pool puts immense selective pressure on an already well spread virus to find a pathway to remain infective. The virus’ that survive to reproduce in a host will be ones that pass longer distances in air, last longer on surfaces, appear benign to immunity functions etc...
It is troublesome, but the medicinal agents available will probably still work on it because those aspects of the virus affected aren’t, as far as I know, under the same suite of components on the exterior of the virus delivery package that are associated with meddling in the immune response.
So HCQ, ivermectin, and other non-vaccine meds should work.