Thanks for that.
Yep. Double masked and still catching Covid.
Strange here under “Laboratory Methods”:
>>”At least two positive controls, eight negative controls (serum specimens obtained before July 2019), and four blanks (no serum) were included in every plate.”<<
I wonder why they had to go all the way back to before July 2019 for these (what type of serum specimens?)negative controls?
Was COVID here earlier than we knew? Not really sure what I am looking at but that before July 2019 seems troubling.
Looking at the supplementary appendix (linked to in the article) - They were doing SARS-CoV-2 whole-genome sequencing at least in December 2019 see page 9 in the PDF - document page 8 https://www.nejm.org/doi/suppl/10.1056/NEJMoa2029717/suppl_file/nejmoa2029717_appendix.pdf
further on page 12 - shows a table of Mutation Profile [Relative to Participant Data Wuhan Ref Genome]
Then there’s this: https://artic.network/ncov-2019 scroll to the end for the acknowledgments.
Hope someone can make sense of this.
> Was COVID here earlier than we knew?
I know more than one person who was sick in December 2019. My son had the strange body rash in November of 2019 (which is why I think I had or still have the antibodies. I need to get the test to determine that.
-SB
https://freerepublic.com/focus/chat/3907739/posts?page=360#360
The study population “From May 12 to July 15, 2020, a total of 1848 of 3143 eligible recruits (58.8%) across nine recruit classes were enrolled in the CHARM study”.
Not surprised that negative controls were from July 2019. To be sure of negative, and to match the season.