In the US, it looks like there are 2 ivermectin products marketed for human consumption, under the brand names Sklice, Soolantra, Stromectol.
https://www.pdr.net/drug-summary/Stromectol-ivermectin-391
Ivermectin/Soolantra Topical Cream: 1%
Ivermectin/Stromectol Oral Tab: 3mg
Sklice Topical Lotion: 0.5%
The topical form is labelled for lice, scabies, and rosacea, and NOT for consumption.
***Overall the drug is metabolized by the liver and liver function should be evaluated prior to use.***
Oral Route
Following oral administration, ivermectin is well absorbed with plasma concentrations proportional to the dose. The effect of food on the absorption of ivermectin has not been determined, therefore the drug is recommended to be taken on an empty stomach with water.
Topical Route
Ivermectin lotion
After a single application of ivermectin lotion, systemic concentrations are much lower than those observed after oral administration of ivermectin at a dose of 165 mcg/kg PO. The mean Cmax and AUC from time zero to the time of last measurable concentration were 0.24 +/- 0.23 ng/mL and 6.7 +/- 11.2 hour x ng/mL, respectively.
Ivermectin cream
After 2 weeks of treatment with ivermectin cream, the Tmax was 10 +/- 8 hours, the Cmax was 2.1 +/- 1.04 ng/mL and AUC was 36.15 +/- 15.56 ng x hour/mL. At the end of the 52-week treatment period, there was no plasma accumulation of ivermectin. The terminal half-life was 6.5 days (155 +/- 40 hours) in patients receiving a once daily cutaneous application of ivermectin cream for 28 days.
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Will dig for veterinary dosage forms later.
Excellent research!
This has been my position from the start. It is rare for topical treatments to work effectively systematically. LittleLinda brought up the issue of nicotine patches; it occurred to me while going to bed that in the case of the patch working systematically the patient is already saturated with nicotine; you can smell it on a smoker. The nicotine in the patch is intended to replace smoked tobacco as a source of nicotine to help avoid smoking hazards involved in the addiction. Using an Ivermectin patch, so to speak, would seemingly fail since the patient's body would not already be saturated with Ivermectin.