Interesting point! I've been hanging onto this Meme that seems to go fairly well with your sauce... Thanks for posting!
~Easy
SARS-CoV-2 appears to be a man made chimeric virus
Here is the blueprint for Modifying (man made) SARS-Cov based Virus
Published in PNAS (Proceedings of the National Academy of Sciences of the United Strates of America) March 14, 2016
https://www.pnas.org/content/113/11/3048
SARS-like WIV1-CoV poised for human emergence
From the first paragraph of this article:
“This manuscript describes efforts to extend surveillance beyond sequence analysis, constructing chimeric and full-length zoonotic coronaviruses to evaluate emergence potential. Focusing on SARS-like virus sequences isolated from Chinese horseshoe bats, the results indicate a significant threat posed by WIV1-CoV. Both full-length and chimeric WIV1-CoV readily replicated efficiently in human airway cultures and in vivo, suggesting capability of direct transmission to humans.”
And from the results summary in this article:
Using the SARS-CoV infectious clone as a template (7), we designed and synthesized a full-length infectious clone of WIV1-CoV consisting of six plasmids that could be enzymatically cut, ligated together, and electroporated into cells to rescue replication competent progeny virions (Fig. S1A). In addition to the full-length clone, we also produced WIV1-CoV chimeric virus that replaced the SARS spike with the WIV1 spike within the mouse-adapted backbone (WIV1-MA15, Fig. S1B). WIV1-MA15 incorporates the original binding and entry capabilities of WIV1-CoV, but maintains the backbone changes to mouse-adapted SARS-CoV. Importantly, WIV1-MA15 does not incorporate the Y436H mutation in spike that is required for SARS-MA15 pathogenesis (8). Following electroporation into Vero cells, robust stock titers were recovered from both chimeric WIV1-MA15 and WIV1-CoV.
And the connection to Wuhan Labs in China is highlighted in the
Acknowledgments
We thank Dr. Zhengli-Li Shi of the Wuhan Institute of Virology for access to bat CoV sequences and plasmid of WIV1-CoV spike protein. Research was supported by the National Institute of Allergy and Infectious Disease and the National Institute of Aging of the NIH under Awards U19AI109761 and U19AI107810 (to R.S.B.), AI1085524 (to W.A.M.), and F32AI102561 and K99AG049092 (to V.D.M.). Human airway epithelial cell cultures were supported by the National Institute of Diabetes and Digestive and Kidney Disease under Award NIH DK065988 (to S.H.R.). Support for the generation of the mice expressing human ACE2 was provided by NIH Grants AI076159 and AI079521 (to A.C.S.).
And an interesting side note:
National Institute of Allergy and Infectious Disease (NIAID) is managed by Dr. Anthony Fauci, in case you were wondering if he had any connection to this.
My assessment is that the PNAS article indicates strongly that NIH National Institute of Allergy and Infectious Disease, managed br Dr. Anthony Fauci, and the Wuhan Institute of Virology, managed by Dr. Zhengli-Li Shi cooperated to create what ultimately became the chimeric virus SARS-CoV-2 (Covid-19) pandemic.
https://www.pnas.org/content/113/11/3048
My further assessment is that the gop-foreignaffairs report is investigating the Chinese Communist Party (CPP) for malfeasance, but apparently not interesting in understanding where this virus originated, they are only interested in blaming CCP for the cover up.
HOUSE FOREIGN AFFAIRS COMMITTEE MINORITY STAFF INTERIM REPORTHOUSE FOREIGN AFFAIRS COMMITTEE MINORITY STAFF INTERIM REPORT
Carol Barr, wife of Representative Andy Barr, dies
(WYMT) - Eleanor Carol Barr, the wife of U.S. Representative Andy Barr, died suddenly on Tuesday night, according to a statement released by Congressman Barr’s Chief of Staff Mary Rosado.
Congressman Barr, a Republican representing Kentucky’s 6th Congressional District, married Carol in 2008. She had previously served as the executive director of the Henry Clay Center for Statesmanship in Lexington.
Together they had two daughters, Eleanor and Mary Clay.
RIP
Interesting point! I've been hanging onto this Meme that seems to go fairly well with your sauce... Thanks for posting!
~Easy
Interesting!
Pinging Lady Doc and greeneyes to 421 for comments.
ThankQ for posting this:
SARS-CoV-2 appears to be a man made chimeric virus
Here is the blueprint for Modifying (man made) SARS-Cov based Virus
Published in PNAS (Proceedings of the National Academy of Sciences of the United Strates of America) March 14, 2016
https://www.pnas.org/content/113/11/3048
SARS-like WIV1-CoV poised for human emergence
From the first paragraph of this article:
“This manuscript describes efforts to extend surveillance beyond sequence analysis, constructing chimeric and full-length zoonotic coronaviruses to evaluate emergence potential. Focusing on SARS-like virus sequences isolated from Chinese horseshoe bats, the results indicate a significant threat posed by WIV1-CoV. Both full-length and chimeric WIV1-CoV readily replicated efficiently in human airway cultures and in vivo, suggesting capability of direct transmission to humans.”
And from the results summary in this article:
Using the SARS-CoV infectious clone as a template (7), we designed and synthesized a full-length infectious clone of WIV1-CoV consisting of six plasmids that could be enzymatically cut, ligated together, and electroporated into cells to rescue replication competent progeny virions (Fig. S1A). In addition to the full-length clone, we also produced WIV1-CoV chimeric virus that replaced the SARS spike with the WIV1 spike within the mouse-adapted backbone (WIV1-MA15, Fig. S1B). WIV1-MA15 incorporates the original binding and entry capabilities of WIV1-CoV, but maintains the backbone changes to mouse-adapted SARS-CoV. Importantly, WIV1-MA15 does not incorporate the Y436H mutation in spike that is required for SARS-MA15 pathogenesis (8). Following electroporation into Vero cells, robust stock titers were recovered from both chimeric WIV1-MA15 and WIV1-CoV.
And the connection to Wuhan Labs in China is highlighted in the
Acknowledgments
We thank Dr. Zhengli-Li Shi of the Wuhan Institute of Virology for access to bat CoV sequences and plasmid of WIV1-CoV spike protein. Research was supported by the National Institute of Allergy and Infectious Disease and the National Institute of Aging of the NIH under Awards U19AI109761 and U19AI107810 (to R.S.B.), AI1085524 (to W.A.M.), and F32AI102561 and K99AG049092 (to V.D.M.). Human airway epithelial cell cultures were supported by the National Institute of Diabetes and Digestive and Kidney Disease under Award NIH DK065988 (to S.H.R.). Support for the generation of the mice expressing human ACE2 was provided by NIH Grants AI076159 and AI079521 (to A.C.S.).
And an interesting side note:
National Institute of Allergy and Infectious Disease (NIAID) is managed by Dr. Anthony Fauci, in case you were wondering if he had any connection to this.
My assessment is that the PNAS article indicates strongly that NIH National Institute of Allergy and Infectious Disease, managed br Dr. Anthony Fauci, and the Wuhan Institute of Virology, managed by Dr. Zhengli-Li Shi cooperated to create what ultimately became the chimeric virus SARS-CoV-2 (Covid-19) pandemic.
https://www.pnas.org/content/113/11/3048
My further assessment is that the gop-foreignaffairs report is investigating the Chinese Communist Party (CPP) for malfeasance, but apparently not interesting in understanding where this virus originated, they are only interested in blaming CCP for the cover up.
HOUSE FOREIGN AFFAIRS COMMITTEE MINORITY STAFF INTERIM REPORTHOUSE FOREIGN AFFAIRS COMMITTEE MINORITY STAFF INTERIM REPORT