[GingisK]

No sir, the Constitution applies ONLY to the Federal government. YOU are not controlled by the Constitution, nor are the owners of any company.

[Olog-hai]

This Constitution, and the laws of the United States which shall be made in pursuance thereof; and all treaties made, or which shall be made, under the authority of the United States, shall be the supreme law of the land; and the judges in every state shall be bound thereby, anything in the Constitution or laws of any state to the contrary notwithstanding.

— Article 6, second paragraph

There is far more than that establishing Constitutional supremacy. States that make laws in defiance of the Constitution are in rebellion, particularly when those laws are socialistic (see the Guarantee Clause of Article 4 Section 4 in particular).