We have been using prone ventilation for severe and refractory ARDS for a long time. It is not the easiest thing to accomplish. While it does increase oxygenation on ABG, there is no study that demonstrates improved outcomes at 30 days (which is the gold standard in ICU management). This has long been studies.
While I do it occasionally when I literally have nothing else to offer, there is significant issues in proning someone. There is increased incidence of blindness, increased incidence of injury related to pressure, and it is nearly impossible to draw labs and monitor appropriately. That being said, it is a Hail Mary last ditch. Oh, and you cannot do CPR on a prone patient — so another pseudo drawback
5. He fails to mention prone ventilation. Anyone who is serious would probe a patient well before a PEEP of +25