The Daily Mail reported. Studies reportedly suggest the drug, leronlimab, calms the overly aggressive immune response that could lead to pneumonia and even death.
“I don’t know the drug personally, but the studies we’re seeing is that, like several drugs we’re trying to use right now in COVID-19, it works predominantly by toning down the immune response that the virus participates in the lung so that the lung doesn’t get injured,” Varga said.
This is critical. There are reports that many, perhaps most, who died from the Spanish Flu were killed by a cytokine storm. My fraternal grandmother died from the Spanish Flu. She was in her early 30s.
From the Scripts Research Institute:
A cytokine storm is an overproduction of immune cells and their activating compounds (cytokines), which, in a flu infection, is often associated with a surge of activated immune cells into the lungs. The resulting lung inflammation and fluid buildup can lead to respiratory distress and can be contaminated by a secondary bacterial pneumonia — often enhancing the mortality in patients.
This little-understood phenomenon is thought to occur in at least several types of infections and autoimmune conditions, but it appears to be particularly relevant in outbreaks of new flu variants. Cytokine storm is now seen as a likely major cause of mortality in the 1918-20 “Spanish flu” — which killed more than 50 million people worldwide — and the H1N1 “swine flu” and H5N1 “bird flu” of recent years. In these epidemics, the patients most likely to die were relatively young adults with apparently strong immune reactions to the infection — whereas ordinary seasonal flu epidemics disproportionately affect the very young and the elderly.
As reported in Science Daily.
https://www.sciencedaily.com/releases/2014/02/140227142250.htm
So taking vitamin C to boost your immune system might not be such a good idea?
[[[leronlimab]]]
These are the “mab” biologics used to control auto-immune disorders. I’m currently on Remicaide for Crohns. Settles down the immune response and puts patients into remission.
These should help patients ride out the virus.
RE: The Daily Mail reported. Studies reportedly suggest the drug, leronlimab, calms the overly aggressive immune response that could lead to pneumonia and even death.
Well, Dr.William Grace said the same thing of hydroxychloroquine. It modulates the over reactive response of the body’s immune system to Covid-19.
The question is this -— which one does it better at a cheaper price? leronlimab, or hydroxychloroquine?