[Mrs. Don-o]

I think high dosages will give you the poopin' miseries. Not so with smaller dose.

I took hydroxychloroquine (Plaquenil) for years for my rheumatoid arthritis: one 200 mg tablet twice a day, every day, with food. Never had the slightest uncomfortable side effect.

Don't know what the dosage would be for CV19 though.

[SeekAndFind]

RE: Don’t know what the dosage would be for CV19 though.

FROM THE STUDY:

SEE HERE:

https://drive.google.com/file/d/186Bel9RqfsmEx55FDum4xY_IlWSHnGbj/view

PATIENT AND METHODS:

COVID-19 patients were included in a single arm protocol from early March to March 16th, to receive 600mg of hydroxychloroquine daily and their viral load in
nasopharyngeal swabs was tested daily in a hospital setting.

Depending on their clinical presentation, azithromycin was added to the treatment.

Untreated patients from another center and cases refusing the protocol were included as negative controls.

Presence and absence of virus at Day6-post inclusion was considered the end point.

[SeekAndFind]

RE: Don’t know what the dosage would be for CV19 though.

FROM THE STUDY:

SEE HERE:

https://drive.google.com/file/d/186Bel9RqfsmEx55FDum4xY_IlWSHnGbj/view

PATIENT AND METHODS:

COVID-19 patients were included in a single arm protocol from early March to March 16th, to receive 600mg of hydroxychloroquine daily and their viral load in
nasopharyngeal swabs was tested daily in a hospital setting.

Depending on their clinical presentation, azithromycin was added to the treatment.

Untreated patients from another center and cases refusing the protocol were included as negative controls.

Presence and absence of virus at Day6-post inclusion was considered the end point.

[mmichaels1970]

Don't know what the dosage would be for CV19 though.

According to this link:

Chloroquine:

Recommends chloroquine 500 mg PO BID x10 days for treatment of COVID-19 pneumonia of mild, moderate, or severe disease

Hydroxycholoroquine:

The study recommends hydroxychloroquine 400 mg BID load, then 200 mg BID for 4 days
Note this is a shorter course than the 10 day chloroquine course noted above

The University of Michigan COVID-19 guidance document recommends:
Adult dosing: 600 mg PO BID x2 doses (load), then 200 mg PO TID
Pediatric dosing (<18 years): 10 mg/kg (max: 600 mg/dose) PO BID x2 (load), then 3 mg/kg PO TID (max: 200 mg/dose)