Anti-inflammatory Effects in Osteoarthritis
…In vitro studies have shown anti-inflammatory effects of calcium fructoborate—a naturally occurring, plant-based, boron-carbohydrate complex—on cellular cultures, and an open-label pilot study (n = 20) found that calcium fructoborate had highly positive effects on OA symptoms. In the 8-week pilot study, OA patients were divided into 2 groups, those with mild and medium forms of OA and those with severe cases. Two assessment measures were used, the Western Ontario and McMaster Universities Arthritis Index (WOMAC) and the Newnham criteria. Mild-to-medium cases received 6 mg/d of supplemental boron; severe cases received 12 mg/d. In subjects with mild and medium OA, average pain reduction was 62.5% in 4 weeks and 70.8% in 8 weeks. In the first 4 weeks, 80% of mild-to-medium OA subjects reduced or eliminated their analgesic (ibuprofen) use. By 8 weeks, 67% had stopped using the nonsteroidal anti-inflammatory drug (NSAID) medication. Joint rigidity disappeared in one-half of the mild and medium OA patients in the first 4 weeks and decreased in the remaining one-half by 87.5% on average. By week 8, all subjects with mild- and medium-level OA were rigidity free. Mobility and flexibility were significantly improved in 71.4% of subjects at 4 weeks and in 77.8% at 8 weeks.
In the severe OA group, average pain reduction was 47.9% at 4 weeks and 64.5% at 8 weeks. In the first 4 weeks, 40% of subjects with severe OA reduced or eliminated their analgesic (ibuprofen) use. By week 8, 75% had quit using their NSAID medication (ibuprofen). Joint rigidity disappeared in one-half of the severe OA patients in the first 4 weeks. In the remaining one-half, joint rigidity decreased significantly, an average rigidity reduction of 50%. Mobility and flexibility were significantly improved in 50% of severe OA subjects at 4 weeks and in 62.5% at 8 weeks.
- FruiteX-B® Calcium FructoBorate (One serving provides just over 5 mg of boron)
- Vibrant Health, Super Natural Boron, Vegetarian Support for Joint and Bone Health (One serving provides 3 mg of boron)
- Move Free Ultra Faster Comfort Tablets (One serving of one pill provides just over 5 mg of boron)
- Move Free Ultra Pro 4 in 1 Joint Support Tablets (One serving of four pills provides just over 5 mg of boron)
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