Prilosec says to use it for no more than fourteen days is a row. LOL I took one a day for fifteen years, and in part of the last year was taking two a day. Then I learned how to prevent my bedtime heartburn and stopped using anything cold turkey. Doubt I’ll ever use it again.
I learned how we are plumbed. In most people, the esophagus connects to your stomach on the right side of your stomach.
Not the front, not the back, not the left side.
So, when you’re lying down, if you’re lying on your right side, stomach acid flows to the valve that normally keeps acid from getting up the esophagus. It’s this leaky valve that allows for heartburn, in my case and maybe yours.
Roll over onto your left side so the acid drains away from the valve. Sleep that way, or, since it takes time for acid to move from one side to the other, stay on your right until you start feeling acid reflux.
On occasion, ie, maybe once a month, alka selzter, or as the other FReeper mentioned some powder and water, during the night knocks out any bothersome acid if needed.
Haven’t used Prilosec or any other treatment in about a year now.