That airlined was not designed to have a large nose opening for cargo ops like the 747.That glaring design flaw completely put it out the race for Fed Ex types.
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Actually, the upper deck is what keeps the A380 from being a desirable freighter.
I loved the story about how Juan Trippe was insistent that they deliver a double deck airliner, and the more Joe Sutter and his team thought about it, they thought it would be a failure if they made it that way. They had a big meeting to convince him, and when the Boeing team went to New York to meet with Juan Trippe, they found out how wide the conference room was and one of their savvy guys brought a length of string with him.
When Trippe began to stubbornly insist that a single deck wouldn't have the room they needed for the number of passengers and they would have to be packed in, the guy brought out the string and stretched it across the room and demonstrated how wide it would be with one deck, and Trippe went along with it.
(I hope I got that right from memory...I read the book some time back!)