Absolutely. We tend to view our movement through the universe in a 2d frame of mind when in reality it is 3d. Not only are we orbiting the sun in our solar system, the solar system is corkscrewing us through stuff in rotation path as our arm of the galaxy circles the galactic center. And I would speculate that besides expanding, all the galaxies are also rotating around the center of the universe just like a galactic center.
All this compounds and greatly raises the probability and chances of running into something we can’t figure on. It’s like saying we have distances in the far north and the far south all figured out by using a Mercator projection map. They are not at all accurate compared to 3d globe distances and real distances. When figuring the movement of our earth we are only figuring in X and Y axis when in reality there are six or more.
And I am a firm believer that there are more than one physical universes, I think they could be just as numerous as the galaxies which adds another influence of movement. We just don’t see them yet and we will refuse to accept this possibility until we physically see it. It’s an antiquated flaw in our logical and reasoning skills that hinders discovery and reality.
Even with a 2D analogue, it's easy to see that it's a problem. Not sure if you've ever seen a spirograph, but even with wobbly pushpins, eventually the pen returns to the same point.