This is one of George Webb’s most interesting videos. He talks about the early days of organized crime in America—booze first, then drugs.
This leads into the CIA’s role, initiated by John Brennan and his desperation to retain control.
https://www.youtube.com/watch?v=-epxW9bJ7rQ
It seemed at the time like it was a long time between the liquor mob in the 30s and the severe drug problems of the 60s and onward, but it was only thirty years. I suppose repeal guaranteed it - they had to find other vices to exploit to replace the alcohol vice.