Sadly, the best intentions cannot prevent things from going to hell once the assets are in someone else's hands. I suspect that a great number of the originators of some charitable orgs would, if given the chance, come back and royally kick some asses over what has been done as a result of their altruism (regrettably, others would take pleasure in the mayhem they inadvertently funded). Alas, "He who dies with the most toys wins just handed all his swag to somebody who will do damned well as they please with it."
I know a gentleman who was given a considerable inheritance contingent upon never leaving the Democrat Party. He has a set of somewhat cartoonish relatives who would happily haul him into litigation if he changed registration, therefore he follows the letter of the pertinent will and testament while not exactly following the spirit of the thing.
Naturally! My thought was more along the lines of money follows money. It does all it can to protect itself, and this by occupying positions of political, industrial, and social power. Every institution is corrupted by money, and this should not surprise anybody.