I had a massive bald faced wasp nest in a small tree in my yard that needed removing. I waited ‘till pitch dark outside anticipating that the wasps would return to the nest after dark. Used a large can of Wasp Killer spray. Squirted continuous spray into small access hole at the base of the nest, thus killing the wasps as they attempted to leave the nest. Hole quickly plugged with dead wasps. However, from the sound of buzzing still within the nest, there were more yet to kill. Waited for another half hour, thus allowing those still alive within the nest to calm down. Got a small stick, punched a hole in the paper thin side and closer to the top of the nest, then resumed spraying into that hole, killing the remainder of those pesky critters as well. Bald faced wasps are VERY NASTY, aggressive critters, not to be fooled with during day light hours. One does what he has to do.
Yes, overwhelming force in the form of highly toxic chemicals is totally appropriate when dealing with large numbers of bad-tempered insects. Had a hornet queen start a nest under the eaves of the house one time. I put a stop to that toot sweet!