Septicemia and e-coli usually indicates a failure in the peritoneum. Could have been a slight tear in the colon from a routine colonoscopy. Could have been from diverticulitis. The e-coli joke I get. But the septicemia is the tell.
I’d really like more info on which strain of e coli Hefner had. Hope someone in the press follows up.
He was 92 years old and in poor health, something was going to get him.