[ifinnegan]

“double-whammy”. I love the term double-whammy.

Don’t hear it too much anymore.

Thanks for posting this. I know a lot about bone narrow regeneration.

[WMarshal]

In other news farting in church is frowned upon. No rewards without risk.

[Pearls Before Swine]

I went to the dentist the other day, and it was time for X-rays. They draped a heavy apron over my torso and went at it.

I don’t know how much shielding is needed to protect astronauts, but could a similar suit be worn? It would cost a bit to thrust it into orbit, but once weightless, wouldn’t impede the astronauts’ movement during the trip.

Or, is the problem energetic cosmic rays which simple measures won’t stop?

[ifinnegan]

In vitro and in vivo assessment of direct effects of simulated solar and galactic cosmic radiation on human hematopoietic stem/progenitor cells

Future deep space missions to Mars and near-Earth asteroids will expose astronauts to chronic solar energetic particles (SEP) and galactic cosmic ray (GCR) radiation, and likely one or more solar particle events (SPEs). Given the inherent radiosensitivity of hematopoietic cells and short latency period of leukemias, space radiation-induced hematopoietic damage poses a particular threat to astronauts on extended missions. We show that exposing human hematopoietic stem/progenitor cells (HSC) to extended mission-relevant doses of accelerated high-energy protons and iron ions leads to the following: (1) introduces mutations that are frequently located within genes involved in hematopoiesis and are distinct from those induced by γ-radiation; (2) markedly reduces in vitro colony formation; (3) markedly alters engraftment and lineage commitment in vivo; and (4) leads to the development, in vivo, of what appears to be T-ALL. Sequential exposure to protons and iron ions (as typically occurs in deep space) proved far more deleterious to HSC genome integrity and function than either particle species alone. Our results represent a critical step for more accurately estimating risks to the human hematopoietic system from space radiation, identifying and better defining molecular mechanisms by which space radiation impairs hematopoiesis and induces leukemogenesis, as well as for developing appropriately targeted countermeasures.

www.nature.com/leu/journal/vaop/ncurrent/abs/leu2016344a.html

[plain talk]

Lead shields

or

robots

[mrsmith]

Doesn’t jibe with evidence from experience. But worth looking into.
Wow, one cosmonaut has almost two years’ cumulative time in space- that’s bizarre to imagine.

[Kickass Conservative]

I wonder why my Oncologist never asked me if I was an Astronaut when he Diagnosed my Leukemia.

[miniTAX]

cell and mice experiments, doses and small effects, unfalsifiable and irreproducible extrapolation to humans + wild media claims and grand press release = junk science.
Typical of the hysterical radiophobic propaganda long ago debunked by real life (see Ramsar, Tapei cobalt buildings, guarapari beaches, etc, etc).

[Prospero]

bft