The Declaration of Independence does not defend the right to disband governments for any reason.
"Light and Transient causes" are in the eyes of the beholder. The Southern States considered their causes very seriously. They regarded actions and efforts from the rest of the union to be commensurate with threats to their livelihood. Something most people take pretty seriously, even today.
They also recognized that New England was robbing them blind financially, and that since the Robber Barons of New England basically controlled the government in Washington D.C., (As it still is today) the only way they could get out from under them was through Independence.
They had representation in the Congress to deal with Tariff issues.
The Declaration of Independence recognized the natural right of rebellion against LEGITIMATE dangers, not imaginary ones.
What you are advocating is anarchy.
And do you think the Confederate States would have allowed one of their States just to leave the Confederacy if it 'felt like it'?
So, the only people who actually had a right to rebel under the principals of the Declaration of Independence and natural law were the SLAVES, NOT THE SLAVE OWNERS.