We tried one of those air purifiers that produced ozone.
Mrs. Joe's people spent centuries on the plains (Chippewa), my people spent centuries on the water (seafarers and fishermen, farmers in the tidewater).
We both got downright bitchy with the air purifier going.
Edgy.
The feeling you get before a real butt-kicking storm.
We figured out the ozone (harbinger of a coming storm) was the culprit, shut off the machine, aired out the house and returned to normal domestic tranquility.
YMMV!
They can also triggering coughing fits. So can Mold.