Cary Grant. And among funny women, Lucille Ball was a classic beauty.
It's a common belief that a person who isn't naturally good looking - or isn't treated as good-looking in youth - is likely to seek positive attention by being funny or interesting. This is intuitively believable.
However, the number of counter-examples raises the question of whether this is simple a myth, rather than a mostly- or often-truism.
George Clooney is handsome and he is funny in the Coen Brothers movies. There are probably more beautiful women who are funny than handsome men who are funny, such as:
Diane Keaton
Jennifer Anniston (not a big fan of her rom-coms but she can make you laugh)
Carole Lombard
Jennifer Jason Leigh (hilarous in The Hudsucker Proxy channeling Rosalind Russell and Katharine Hepburn)
Mary Tyler Moore
Valerie Harper
Shelley Long
Emily Blunt (beautiful and funny in The Devil Wears Prada)