It was a monumental butt-thrashing, as I recall.
Didn’t seem to hurt in 2010 (we took back the house).
Didn’t seem to hurt in 2012 (we took more seats in house, got some fresh conservative blood in the Senate (Cruz and Lee) and we only lost POTUS because Romney was a wishy washy mess).
Didn’t seem to hurt in 2014 (we remained in control of the house and re-took the Senate)