Drove across the UP on Route 2 back in 1965...can’t imagine it has changed much since then...real nice relaxing drive.
Another god outdoor/semi-wilderness drive is the Blue Ridge Parkway for a little over 400 miles from western North Carolina up to northern Virginia. It ends about 80 miles west of Washington, DC. Makes for a very pleasant, scenic 3 day drive. It’s particularly fun on a motorcycle.