Vancomycin seems to be the only thing out there for C.Diff. After weeks of treatment with vancomycin, the C.Diff goes away for a several weeks, then returns with a vengeance.
There's a more recent drug now - Dificid (Fidaxomicin), as was mentioned in this thread from early July - FDA grapples with oversight of fecal transplants.
My mom has been fighting C-diff for some time now. Her physician is sticking with Vancomycin but there doesn't seem to be any progress.