Yes , I am aware , and dutifully wash my hands before and after working with the plant. It is a solanaceous family member ( tomato ,potato, etc.)
I am aware that the plant, leaves , and seeds are toxic in consumption , although it makes for a beautiful low flowering shrub. It is pot bound and will not spread.
Medicinal in that it is psychotoxic , can cause hallucinations, is a diuretic and causes diarrhea, depending on quantity.
It is known as Jimsonweed, Jamestown weed , thornapple, etc.
It also had an historic usage in that local women cooks, hired by the Hessians ,cooked a stew with Datura leaves, prior to the Battle of Yorktown.
Incidently , it was the only significant battle of the American Revolution that the colonials won , and was the turning point of the Revolutionary War .
But yes , I handle plants with care, and conduct frequent hand washings. The upright lily-like blooms are beautiful .