Out of pocket today for a bit. Whatever will my OC do!
Found this little nugget about Ebola:
http://jvi.asm.org/content/77/18/9733
Cytotoxicity appears to be precisely controlled by a mechanism involving down-regulation of GP expression through a transcriptional RNA editing event by the viral polymerase. The importance of this phenomenon was shown by use of a reverse genetics system for replicating Ebola virus in which a mutation that increases the level of full-length GP expression is significantly more cytotoxic than the wild-type virus