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Not sure about DNA on the Basques, but their language is an isolate in Iberia, but isn't prehistoric per se, that is, there's no evidence that they didn't enter the peninsula only shortly before or even after the Romans. Their predominant blood type is O, which may not be surprising:

America B.C.
by Barry Fell
(1976)
find it in a nearby library
A fascinating letter I received from a Shoshone Indian who had been traveling in the Basque country of Spain tells of his recognition of Shoshone words over there, including his own name, whose Shoshone meaning proved to match the meaning attached to a similar word by the modern Basques. Unfortunately I mislaid this interesting letter. If the Shoshone scholar who wrote to me should chance to see these words I hope he will forgive me and contact me again. The modern Basque settlers of Idaho may perhaps bring forth a linguist to investigate matters raised in this chapter. [p 173]

A lot of yDNA, R1b.

Basque DNA Project

There are many/mostly R1b amongst the Gauches on the Canary Islands.

Guanches-Canary Islands-DNA Project- Background

"The Guanches are the mysterious natives of the Canary Islands. They were conquered by the Spaniards during the turn of the 15th century. Tall, blond and blue-eyed, the Guanches have long intrigued the anthropologists, for blond natives are rarity. According to the reliable Encyclopedia Britannica, the Guanches "are thought to have been of Cro-Magnon origin... and had a brown complexion, blue or gray eyes, and blondish hair.""

" Indeed, the Guanches are deemed to be related to the Berbers of neighboring Morocco, who are, likewise, tall, blond and blue-eyed when unmixed with the Arab majority. Other specialists, however, believe that the Guanches are related to the Celts of Western Europe, the early realm of these races. No matter what, the Guanches represent a unique opportunity of studying the early peoples of this region.