Have taken a small whitetail with my Dan Wesson with the 8’ barrel with a very similar load. It really is a hand cannon and very accurate (all the rage at silhouette shooting in the 70’s), but recently I shrunk it down with the snubby barrel and tiny concealed carry grips and it rides comfortably all day long.
I like the safeties on my revolver much better than the ones on my semi-autos.
The modern revolver is Inherently safe. Mine are made by S&W, Ruger and Colt(SAA only safe with 5 rounds). The beauty is you don’t have any safety devices to shut off. Double action you just shoot. Single action you cock and shoot. No grip safeties. No safety ambidextrous or not. Don’t need em.
I have never handled a dan Wesson. I do know they are adjustable for barrel length and barrel/cylinder gap. Cool concept.
I have taken 2-180lb does with a Ruger redhawk (the old style not the super model ) in .44 mag. 1 at 50yd and 1 at 75 yds. Both went down for good after 1 shot. I recovered no bullets. The 75 yd shot was extreme quartering away. Suffice it to say that it traversed pretty much the whole deer and exited the chest. This was a 1200fps 240 grain hollow point Sierra pill. My load once again with IMR-4227(I forget the weight). Off a bench I have made 1 hole three shot groups. Very nice trigger for a stock piece. My back tells me not to carry it any more. I slip a .380acp Colt mustang in my vest for a coup de gras and for varmints. Gonna switch to a Ruger LCP or lc9. Much lighter.