The grip angle for one. The lack of a tactile loaded chamber indicator is another.
I have had similar issues with the Glock pistols, so I just ordered two backstrap ‘adjustment’ devices which cant the grip more to the 1911 shape by adding to the back up higher than the middle of the grip. I look forward to testing them on my 40 cal Glocks first. They currently ship two for the price of one, in black or a light coyote tan. Company CEO is a cop in OH. The shape allows a better ‘purchase’ on the grip and keeps the hand closer to the bore axis for control and aiming. The one I tried at our range seemed to reduce felt recoil muzzle flip, too!