I read a biography of Lewis and Clark awhile back (?Undaunted Courage?). In it there was a basic culture clash between white guys who thought that manhood meant growing up to be prosperous, and well-respected for leadership in the community, and native guys who thought that manhood meant being a warrior. The whole idea of having peace with other tribes, including the white one, seemed ludicrous to young tribesmen, because it would basically mean that they would never have a chance to be real men. Peace was for wusses. If those were the underlying assumptions of the two groups of men, I can see why peace and understanding didn’t happen.
Kind of sounds like the clash between British and German cultures in the 1930s.