2) mutations are overwhelmingly too subtle to be selectable;
3) biological noise and survival of the luckiest overwhelm selection;
4) bad mutations are physically linked to good mutations, so that they cannot be separated in inheritance (to get rid of the bad and keep the good).
I don't think that person knows about polyploidy or any of the other mutations that involve duplication of genetic code.
I think that person doesn't understand a lot about genetics.