I use PCLinuxos it works great with just about everything i throw at it
www.pclinuxos.com
There are three main categories: Debian-based (Ubuntu and variants), RPM-based (Mandriva and variants and Slackware-based (Gentoo and variants). Every Linux distro will have a GUI interface layered on top of the X Windows system: GNOME, KDE, XFCE, and LXDE and assorted other window managers. The first four are DE’s. Linux uses a unified package manager to manage and handle updates for both the system as a whole and for individual packages. There are different command-line package managers and GUI front-ends for them like Synaptic and YAST. Linux’s greatest asset is its rock-solid stability and computing ease of use. That explains why its been around so long and offers an amazing variety of distros to cater to every interest and serve every possible need.
We’ll see what its going to be like for it when the next twenty years come around.