Yes, he was very anti-Hamilton and his policies ending up causing depression.
No, this has been completely disproven. I hate his policies, but Peter Temin (The Jacksonian Economy) has shown that international silver flows---which dried up in the early 1830s and then the effects circled the globe to raise British interest rages---cause the depression. Virtually all economic historians, including Libertarians like Richard Timberlake, pretty much give Jackson a pass.