The Bible disagrees with you.
St Paul made clear that via Adam, ALL CREATION FELL. And, we know from Scripture that ALL CREATION groans, yearningly, desperately hoping and waiting for the day of the manifestation of the sons of God--evidently because of their ruling and reigning with Christ toward the practical effective of relieving ALL CREATION OF THE POLLUTIONS OF SIN THROUGH ADAM.
BTW, I don't think your vat of 'holy' water etc. would avail much. The Blood and Name of Jesus applied in Spirit-led spiritual warfare would--as Guy Malone's documented 400+ cases illustrate.
For example, those angels who DID NOT fall were created by God. But they aren't polluted with the sin of Adam.
This kind of language needs to stop in all discussions. "The Bible" doesn't disagree with me: YOU disagree with me. Your interpretation of Sacred Scripture is not "The Bible", it's your interpretation. Now, it's perfectly fine that your interpretation and mine conflict. Your interpretation is not synonymous with Holy Writ, NEITHER is mine.
I don't even acknowledge that non-earth born physical life that possesses a rational soul exists, at best it's a theory and if some wild LSD induced fantasy turns out to be true we're going to have to rethink a few things.
Romans 8:22... is St. Paul saying what you think he's saying? St. Paul is saying LIFE SUCKS FOR EVERYONE even the elect so don't go all crazy expecting earthly existence to be wine and thornless roses. If Martians show up we're going to have to reconsider "all have sinned" before we get all preachy. But I'm unconvinced that Martians or anybody else other than angels and demons are "out there".
As for effectiveness of holy water... if there are nephilim running around it's not gonna just be spiritual warfare, that's why my sanctuary lamp would be jet powered and my relics would be attached to a baseball bat. If you want to etch "The Name of Jesus" on a machine gun that would probably be a good idea too. And for goodness sake I'm joking in the first place.