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And, even though we might imagine faster than light travel, so far there has been not the slightest hint that such a thing is possible.

We're like paramecia here who are referring back to our very limited understanding of the laws of physics and finally deciding that, no, there is NOTHING, NO WEAPON AT ALL, that humans could possibly have that they could use against us.

I'm not as confident as you are that creatures billions of years more advanced than us would have no way of getting to us and destroying us if they so desired.

As far as no species (on earth) ever lasting a billion years, that rule of thumb may not apply to advanced species that have engineered themselves into some highly optimized form and spread out over vast regions of space and time.