His first marriage was to dance instructor Doreen Alderman and lasted from 1982 to 1990 during which time they had one child, Spencer, now 26, an actress.
He married stripper Leigh-Anne Csuhany in 1992. They parted after he claimed she was abusive and had beaten him up.
During this marriage, Grammer had a daughter out of wedlock, Greer Kandace, now 18, with hair and makeup stylist Barrie Buckner.
Grammers life has been marked by tragedy. When he was 13 his estranged father, Allen, was gunned down in a random attack by a psychopath.
His younger sister, Karen, was raped and stabbed to death 35 years ago by a gang of teenagers, a tragedy from which he never fully recovered and which led him into a self-destructive spiral of drink and drugs.
In 2008 he had a near-fatal heart attack.
He also battled the loss of his close friend, David Angell, the creator of Frasier, who died with his wife Lynn aboard American Airlines Flight 11 when it was crashed into the World Trade Centre in New York during the 9/11 attacks.
That's interesting. I had not heard that before.