The author doesn’t even speculate on how water from a river in Greece could get to Persia to poison Alexander.
Plus, the article indicates they've not even sampled the water from that stream. It's all sheer speculation. They also conflate mythology about the stream in Hades and its effects on the Gods with the speculation about actual stream that according to legend was the source of the mythical river.
They might think about Occam's Razor and look at all those years on the march or the very hard party life he enjoyed after his conquests or someone using a poison available in Babylon as more likely causes.
That is a puzzle, isn’t it? Made no freakin’ sense at all to me, but figured, hey, great headline. :’)
Forget it, he's on a role.