Heres my prediction for LOST:
Global warming causes the ice caps to melt. Lost polar bears float on broken ice chunks which are drawn magnetically to the island due to trace iron trailings embedded in the ice from mining activities in Alaska. Famished, the bears land on the island and eat Kate, Hurley, Sawyer, Jin, Jack, etc. just before sinking into the depths of the rising ocean.
The final scene shows Locke cruising on his wheelchair turned jet boat toward the newly revealed Antarctic continent where Ron Hubbard has secretly been controlling the world with his e-meter.
Remember...you heard it here first!
I have a prediction too, and I think I finally got into the writer's heads.
In the last scene the camera pans back and reveals that all of the cast members are mental patients in a hospital. They are all sitting at a table playing one of those reality board games where you draw a card and act out the part in your own imagination. The entire series was a figment of their imaginations and it ends when Hurley quits and wants some more fried chicken.