Megastars burn through their fuel at a very rapid rate. For a Blue Giant star you are talking about only a few million years before it supernovas.
Speaking of supernova, I shot this supernova remnant last week. It was a series of 16x150 second exposures, calibrated, aligned and stacked.
This supernova exploded about 7000 years ago, and is about 2,000 light-years distance from earth.
Veil Nebula NGC 6992