Looks like they lived in the DC area or visited relatives who lived there. The two ladies are standing under the cherry blossoms, with the Potomac behind them. The Skyline Drive reference is the roadway that goes into the rural area of Virginia, noted for its lovely fall foliage.
DC area is what I thought too.
Could they be wearing Easter bonnets? The hats seem pretty fancy. Easter was on March 24 in 1940 and on April 13 in 1941. Which date is more likely for the cherry blossoms?
The photos are really sharp. I am guessing someone in that family owned a proffesional camera, maybe a 4X5 inch sliding plate type.