There are hardware problems, especially memory, that will cause EUEs. Heat will do it also, and blowing out a system has cured some really hard-to-find problems.
Software issues start with spyware and virus problems and progress to Windows becoming unstable. Video drivers can also cause problems. Was your system updated by M$ last Tuesday? Ruh Roh.
Now, if you are running new work units the natural regression patterns will find that half of work units will fail. Its natural and will get better as out-of-bounds solvations are excluded.
When in doubt, go ahead and erase the existing work files and reload F@H. Better to lose one WU than a dozen.